An integrated mass spectrometer system for multi-stream fermentation off gas analysis

Measures off gas and vapour concentrations, OUR, CER, RQ  from multiple reactors

The Hiden QIC BioStream is a complete, multi-stream gas composition monitoring system.Capable of analysing gas streams at flow rates from 4 ml/min up to 10 L/min. The system is suited to a range of applications including fermentation off-gas analysis, biogas production monitoring and bio-enzyme production.

Overview

The system features Hiden’s state-of-the-art “Proteus” Multi-stream selector valve coupled with a precision, ultra-stable triple filter mass analyser. Fast data acquisition and low internal dead volume allows switching times of less than 10 seconds per stream. 

Hiden’s QGA Professional quantitative gas analysis software features automatic calibration routines for accurate quantitative analysis. Gas/vapour mass spectral libraries and automatic subtraction of spectral overlaps allow for precise fragmentation pattern recording.

Features

  • 20, 40 and 80 way sample configurations, Integral thermocouple / heater up to 120°C
  • Robust, flexible, heated QIC direct inlet <500ms response to gases / vapours
  • Gas flows from 0.01 10 l / min from 10 mbar to 2 bar, 100 amu profile in 2.5s
  • High Sensitivity (to 5 ppb) and Stability (< ±0.5% height variation, 24 h), to 510 amu
  • Zero ‘crosstalk’ for low memory effects, Low dead volume for fast response
  • Novel face sealing technology provides effective seal with long life (>6x106 events)
  • Direct drive, high torque microstepping motor with incremental rotary encoder for home z-position and closed loop motion
  • Motion management including: Bi-directional travel for shortest path, Intelligent acceleration / deceleration, Position maintenance, Error annunciation
  • Soft Ionisation for the analysis of complex organics
  • Windows™ MASsoft control via RS232, RS485 or Ethernet LAN

Specifications

Mass range

200 or 300 amu

High flow options for reactors > 1L

Yes

Low flow options for micro reactors

Yes

Stream selection on the fly 

Yes

OPC connectivity

Yes

Number of streams

20, 40 or 80

Measures

O2, CO2, N2, C2H6O, CH4O and other gases/vapours

OUR/CER/RQ (Method 1)

Includes flow rate measurement

OUR/CER/RQ (Method 2)

Uses ratio, without measured flow

Mass flow meter option

Stream flow rate measured

Mass flow meters

Single or dual

Mass flow meter ranges 

0-500 atm cc/min and 0 -12 atm litres/min 

Sample flow required (Low flow)

< 4 atm. cc/min

Sample flow required (High flow)

> 50 atm. cc/min